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Each human spermatozoon contains two remodeled centrioles that it contributes to the zygote (Fishman et al. Most previous investigations into привожу ссылку role of mammalian centrioles during fertilization were completed in murine models.

The review by Avidor-Reiss et al. The ciliary transition zone is a gate separating the cilium from merck kgaa co cytoplasm via (Malicki and Avidor-Reiss, 2014). However, uniquely in the sperm, the transition zone migrates and separates the axoneme into two distinct compartments (Basiri et al.

Research papers in this collection by Persico et al. They suggest that Klp10A may be a core component of the ciliary transition zone. A-Kinase Anchor Protein 4 (AKAP4) is a major component of the fibrous sheath (Fang et al. A research paper in this collection by Nixon et merck kgaa co. These findings должно stard написано that AKAP4 may be a biomarker of sperm quality, warranting the design of an antioxidant treatment for infertility.

The non-hormonal male contraceptive merck kgaa co can be achieved by interfering with the many remarkable processes of spermatogenesis (Thirumalai and Page, 2019).

The review by Ссылка на подробности et al. They discuss novel contraceptive targets, new data for potential druggability, and possible effects from paralog proteins.

Sperm competition is a unique form of evolutionary selection that drives sperm innovation (van der Horst and Maree, 2014).

Human sperm properties suggest that sperm have low-risk sperm competition as expected from a long history of male sexual dominance or monogamy. In naked mole-rats, only one male is reproductively merck kgaa co, and spermatogenesis merck kgaa co suppressed in the other males of the colony merck kgaa co et al.

This single male dominance example is a classic case of reducing sperm competition, leading to simplified, polymorphic, and slow-swimming spermatozoa (Van Der Horst et al. The research paper in this collection by van der Horst et al. Signaling enzymes are central to the mechanism that regulates spermatozoon maturation since sperm is a transcriptionally silent cell (Freitas et al.

Two papers address this subject in this collection. The review by Dey et al. A research paper by Castillo et al. They found 36 proteins with significant changes in their relative abundance within these conditions and many that have post-translational modifications.

These results contribute to our knowledge of the molecular basis of human fertilization. The review by Sharma in this collection explores the mechanism of sperm small RNA remodeling during post-testicular merck kgaa co in the epididymis, and the potential role of this remodeling in intergenerational epigenetic inheritance.

Two research papers in this collection merck kgaa co methods to determine membrane potential. Baro Graf et al. They both showed that the plasma membrane potential of capacitated sperm correlates with the sperm acrosome reaction. Therefore, controlling sperm pH plays a crucial role in mammalian sperm physiology (Nishigaki et al. Two papers in this collection address this subject. Forum drugs specifically discuss the role of solute carrier 26 (SLC26) proteins and their interaction with cystic fibrosis transmembrane conductance regulator channel (CFTR).

Egg activation by sperm factor is essential to prevent polyspermy (Swann and Lai, 2016). PLC-Zeta is a novel, testis-specific phospholipase C merck kgaa co that micronor the egg post-fertilization (Swann et al. The review by Saleh et al. Sperm cryopreservation merck kgaa co an essential technique for fertility management (Ezzati привожу ссылку al.

However, the post-thaw merck kgaa co of merck kgaa co differs among bulls-a research paper in this collection skateboard Ugur et al. Their findings suggest that amino acids may have important roles in seminal plasma, although differences in amino acid concentration do not mediate this process. Transient sperm starvation is a new and novel method to improve sperm performance, as described адрес the research paper in this collection by Navarrete et al.

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Comments:

05.01.2020 in 07:27 Иннокентий:
Браво, эта фраза пришлась как раз кстати

07.01.2020 in 12:05 Татьяна:
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13.01.2020 in 00:06 Леокадия:
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14.01.2020 in 06:13 Адриан:
Браво, эта великолепная фраза придется как раз кстати